JAWS can be set to change tone on HTML tags like strikethrough, but less than a year ago there was quite the debate if it should just change tone automatically without user settings being applied for that, which spawned yet another debate concerning those using assistive tech who cannot hear - since changing tone doesn't help them. Interesting stuff - the discussion I'm quoting is here:

http://webaim.org/discussion/mail_thread?thread=4464