Nope -- that just means that the patch is old enough that there have been other changes to the file in the meantime (the patch is a month and a half old, and we make enough changes in any given week that it's pretty likely a patch won't apply cleanly after a week or two).

I've poked the person who came up with the patch in Bugzilla in order to get her to redo the patch! In the meantime, you can manually patch User.pm by finding the sections in question and copying/retyping the patched bits.