Hmm. How about if I could do this in two different ways? Number one: pick a user and edit all permissions for them. That's nice for admin changes and other stuff which isn't relevant to most members as you pointed out (bonus points if this can be an ajax-y pop-up or a magic section like settings on the beta entry page). Number two: pick any setting (admin, add tag, etc.) or possibly several ones for bulk changes and have the table only display the settings I've selected. Could still be a big clunky table but hey I'm the one who picked too many settings... :)